The parasite can "fight" to kill cancer cells! In January 23rd, the preliminary research professor Chen Xiaoping China Academy of Sciences, Guangzhou Institute of biomedicine and health released caused quite a stir, related articles reported on micro-blog and friends refresh, and ask questions more optimistic pursuit. Recently, the reporter visited Guangzhou two hospitals participating in a clinical trial found that many patients from across the country and their families to come to consult the application group. For the outside world to stir the parasite can cure cancer ", many experts said that the Plasmodium cancer treatment effect remains to be verified on more clinical cases and long time, it is too early to tell.
Field visits
The application in test group patients in Guangzhou
In two hospitals the Plasmodium clinical immunotherapy test respectively is the First Affiliated Hospital of Guangzhou Medical University, Guangzhou Fuda cancer hospital. In the First Affiliated Hospital of Guangzhou Medical University, the reporter found that the relevant ward without consulting the presence of ward, left on the wall telephone consultation, but it is difficult to get through. The corridor posted on the "parasite immune therapy of advanced non-small cell lung cancer clinical research" the display panels, the topic for people, Chen Xiaoping, Ouyang Ming, zhong. According to the latest information, the First Affiliated Hospital of Guangzhou Medical University at present, the project has ended in the group.
In Guangzhou Fuda Tumour Hospital, has a number of applications into the group of patients in the queue. The patient's family told reporters that he is to see the CCTV reported after a special trip to Guangzhou, try holding the idea for immunotherapy of plasmodium."Of course is to be able to cure, but also know that research does not always succeed." The patient said that they are willing to take the risks of treatment, because the patient has no other effective treatment.
The reporter was informed that currently has hundreds of patients from Beijing, Hebei, Hunan and other places of registration of the project, the patient's family told reporters, the biggest difficulty is to obtain accurate and effective information, the network announced part of the registration process and the site does not match.
Real effect
Need enough cases and long time observation
The study on Chen Xiaoping, in a number of articles from the media, the use of "cure" words, which contributed to the rapid stir this topic, also attracted a lot of questions. But the reporter found out, Chen Xiaoping, Zhong two scholars expressed, were not used the term "cure for cancer".
Before the introduction of Professor Chen Xiaoping in an interview with reporters, the method is to treat Plasmodium cancer patients into 1 ml of red blood cells with plasmodium. After observation, in the initial 10 patients, 5 cases were effective, 2 cases could have been cured. Chen Xiaoping stressed that "may be cured", because the validation of a therapeutic effect in medicine, is an important indicator, is also observed in 5 years to see whether the recurrence of cancer. At present, this study, observation of the earliest patients is only about 2 years, said it is too early to cure.
Recently, academician Zhong Nanshan also responded that this therapy is still in the experiment, has not yet reached the stage of conditional approved medication. At present, the study is still a lot of unknowns, there is no sufficient evidence and a sufficient number of cases confirmed the effectiveness of the method, individual cases is not sufficient to explain the problem. "Now seems to have some signs, but a conclusion too early." Guangzhou Fuda Tumour Hospital relevant responsible person said, to observe the treatment effect of cancer requires a longer time, more randomized controlled trials of big data, therefore effectively, there is not an accurate evaluation of the effect of treating cancer of plasmodium.
The United States Duke University cancer biology Dr. Li Zhizhong said, the current study participation is too little, there is no formal clinical studies, so the curative effects and side effects are unknown.Before the clinical data published, some from the media to the public "is an artifact of Plasmodium cancer" is not appropriate, use the word "cure" is a serious misleading.
The focus of questioning
The parasite might be harmful to patients
At present, the network of the research question, mainly focused on the safety and effectiveness of clinical trials and the compliance. To the patients injected with Plasmodium falciparum erythrocyte, whether through the approval of the ethics committee?
Reporter query Chinese clinical trial registration center site found, corresponding to the three hospitals in the treatment of Plasmodium, registered with Plasmodium related research for cancer immunotherapy for a total of three, respectively, by the China registered clinical trials, the ethics committee of the First Affiliated Hospital of Guangzhou medical university ethics committee and Yunnan Kunming Hospital Ethics Committee approval.
Some people worry that in advanced cancer patients and a parasite, will cause greater harm to the patient? Zhong Nanshan also said when interviewed by the media, infected patients will lead to cyclical and other symptoms have a fever. On this question, Professor Chen Xiaoping team said that the side effects of immunotherapy is Plasmodium fever and anemia, but the density of artemisinin to control parasite team at a relatively low level, can make patients with fever, anemia. At the end of the treatment, can remove parasite thoroughly with anti malarial drugs.
Whether artemisinin can control the parasite? The reporter interviewed Guangzhou University of Chinese Medicine professor Xu Qin was invited to participate in the African malaria control project.He said that for injection into human red blood cells mixed in the parasite, as effective as artemisinin, but need to pay attention to if the blood may appear different hemolysis.
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